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Biblioteca (s) : |
INIA Las Brujas. |
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Fecha : |
11/04/2017 |
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Actualizado : |
09/10/2019 |
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Tipo de producción científica : |
Artículos en Revistas Indexadas Internacionales |
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Autor : |
DALLA RIZZA, M.; DIAZ, P.; NARANCIO, R.; CABRERA, A.; FERREIRA, F. |
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Afiliación : |
MARCO DALLA RIZZA VILARO, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay; PAOLA ALEXANDRA DIAZ DELLAVALLE, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay; RAFAEL NARANCIO FERES, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay; ANDREA CECILIA CABRERA BARRIOS, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay; FERNANDO FERREIRA, Universidad de la República (UdelaR)/ Facultad de Química. |
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Título : |
Biomolecules as host defense weapons against microbial pathogens. (Review) |
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Fecha de publicación : |
2008 |
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Fuente / Imprenta : |
Recent Patents on DNA and Gene Sequences, 2008, v.2, no.2, p.82-96. |
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ISSN : |
1872-2156 |
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DOI : |
10.2174/187221508784534186 |
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Idioma : |
Inglés |
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Notas : |
Article history: Received: April 21, 2008 / Accepted: April 29, 2008 / Revised: April 29, 2008. |
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Contenido : |
ABSTRACT.
Antimicrobial peptides have been considered a new source of biomolecules in several fields of research/innovative applications: they would adjust to an ideal behavior seeking to overcome clinician, microbiological, human-animal-plant-environmental concerns. Antimicrobial peptides can be considered as ancient weapons found in living organisms suggesting they have played a fundamental role in his successful co-evolution with pathogens. Acting on microorganism membrane or having intracellular targets, they can also act as effectors of the innate immune response resulting on non-specific mechanisms of action. Two elements have speeded the research on pathogen control alternatives: a verified increase of antibiotic resistance and the relevance of finding amenable environmental compounds in plant health. As a result of its importance, great efforts have been accomplished to find, characterize, combine and synthesize effective antimicrobial peptides. This review intends to emphasize the generation of biomolecules, whether native or synthetic analogues, that have been matter of recent patents. Development of biomolecules suitable for therapeutic scopes and agricultural use have several challenges such as intrinsic toxicity, in vivo stability and suitable formulation contemplating the cost of production. Thus, biotechnological procedures using microbial systems or transgenic crops as plant factories might help to solve these challenges.
© 2008 Bentham Science Publishers Ltd. MenosABSTRACT.
Antimicrobial peptides have been considered a new source of biomolecules in several fields of research/innovative applications: they would adjust to an ideal behavior seeking to overcome clinician, microbiological, human-animal-plant-environmental concerns. Antimicrobial peptides can be considered as ancient weapons found in living organisms suggesting they have played a fundamental role in his successful co-evolution with pathogens. Acting on microorganism membrane or having intracellular targets, they can also act as effectors of the innate immune response resulting on non-specific mechanisms of action. Two elements have speeded the research on pathogen control alternatives: a verified increase of antibiotic resistance and the relevance of finding amenable environmental compounds in plant health. As a result of its importance, great efforts have been accomplished to find, characterize, combine and synthesize effective antimicrobial peptides. This review intends to emphasize the generation of biomolecules, whether native or synthetic analogues, that have been matter of recent patents. Development of biomolecules suitable for therapeutic scopes and agricultural use have several challenges such as intrinsic toxicity, in vivo stability and suitable formulation contemplating the cost of production. Thus, biotechnological procedures using microbial systems or transgenic crops as plant factories might help to solve these challenges.
© 2008 Bentham Science Publishers ... Presentar Todo |
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Palabras claves : |
ANTIMICROBIAL; BIOCONTROL AGENTS; MODES OF ACTION; PEPTIDES. |
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Thesagro : |
AGENTES DE CONTROL BIOLOGICO; ANTIMICROBIANOS; PEPTIDOS. |
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Asunto categoría : |
-- |
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Marc : |
LEADER 02414naa a2200289 a 4500
001 1057010
005 2019-10-09
008 2008 bl uuuu u00u1 u #d
022 $a1872-2156
024 7 $a10.2174/187221508784534186$2DOI
100 1 $aDALLA RIZZA, M.
245 $aBiomolecules as host defense weapons against microbial pathogens. (Review)$h[electronic resource]
260 $c2008
500 $aArticle history: Received: April 21, 2008 / Accepted: April 29, 2008 / Revised: April 29, 2008.
520 $aABSTRACT. Antimicrobial peptides have been considered a new source of biomolecules in several fields of research/innovative applications: they would adjust to an ideal behavior seeking to overcome clinician, microbiological, human-animal-plant-environmental concerns. Antimicrobial peptides can be considered as ancient weapons found in living organisms suggesting they have played a fundamental role in his successful co-evolution with pathogens. Acting on microorganism membrane or having intracellular targets, they can also act as effectors of the innate immune response resulting on non-specific mechanisms of action. Two elements have speeded the research on pathogen control alternatives: a verified increase of antibiotic resistance and the relevance of finding amenable environmental compounds in plant health. As a result of its importance, great efforts have been accomplished to find, characterize, combine and synthesize effective antimicrobial peptides. This review intends to emphasize the generation of biomolecules, whether native or synthetic analogues, that have been matter of recent patents. Development of biomolecules suitable for therapeutic scopes and agricultural use have several challenges such as intrinsic toxicity, in vivo stability and suitable formulation contemplating the cost of production. Thus, biotechnological procedures using microbial systems or transgenic crops as plant factories might help to solve these challenges. © 2008 Bentham Science Publishers Ltd.
650 $aAGENTES DE CONTROL BIOLOGICO
650 $aANTIMICROBIANOS
650 $aPEPTIDOS
653 $aANTIMICROBIAL
653 $aBIOCONTROL AGENTS
653 $aMODES OF ACTION
653 $aPEPTIDES
700 1 $aDIAZ, P.
700 1 $aNARANCIO, R.
700 1 $aCABRERA, A.
700 1 $aFERREIRA, F.
773 $tRecent Patents on DNA and Gene Sequences, 2008$gv.2, no.2, p.82-96.
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Registro original : |
INIA Las Brujas (LB) |
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Registro completo
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Biblioteca (s) : |
INIA Las Brujas. |
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Fecha actual : |
29/03/2021 |
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Actualizado : |
31/03/2021 |
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Tipo de producción científica : |
Trabajos en Congresos/Conferencias |
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Autor : |
NAVAJAS, E.; MACEDO, F.; LEMA, O.M.; LUZARDO, S.; AGUILAR, I. |
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Afiliación : |
ELLY ANA NAVAJAS VALENTINI, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay; FERNANDO LIBER MACEDO, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay; OSCAR MARIO LEMA QUEIJO, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay; SANTIAGO FELIPE LUZARDO VILLAR, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay; IGNACIO AGUILAR GARCIA, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay. |
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Título : |
Accuracy of genomic predictions for carcass and meat quality traits in the Uruguayan Hereford breed. |
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Complemento del título : |
Volume Species - Bovine (beef) 1, p. 636. |
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Fecha de publicación : |
2018 |
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Fuente / Imprenta : |
In: Proceedings of the World Congress on Genetics Applied to Livestock Production, 11., Aotea Centre Auckland, New Zealand: WCGALP, ICAR, 11-16 feb 2018. |
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Páginas : |
6 p. |
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Idioma : |
Inglés |
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Notas : |
Acknowledgements: This work was supported by the Agencia Nacional de Investigación e Innovación (ANII) (grants RTS_1_2012_1_3489 and FMV_1_2011_1_6671), Instituto Nacional de Investigación Agropecuaria (INIA), Sociedad de Criadores de Hereford (SCH), Instituto Nacional de Carnes (INAC) and Asociación Rural del Uruguay (ARU). |
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Contenido : |
SUMMARY.
Genomic selection provides the opportunity of genetic improvement of difficult-to-measure traits, such as carcass and meat traits. This study investigated the accuracies of genomic predictions of carcass and meat quality traits in Hereford with an initial training population of 747 steers. Hot carcass weights, rib eye areas and subcutaneous, fat depths were recorded in commercial slaughterhouses, as well as, the left pistola cut weight and retail product. Shear force and intramuscular fat content were measured in the Longissumus dorsi. |
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Palabras claves : |
Beef cattle; Carcass quality; Genomic selection; Meat quality; Predictability. |
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Asunto categoría : |
L01 Ganadería |
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URL : |
http://www.ainfo.inia.uy/digital/bitstream/item/15399/1/accuracy-genomic-predictions-carcass-and-meat-quality-traits-uruguayan-hereford-breed.pdf
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Marc : |
LEADER 01665nam a2200241 a 4500
001 1061877
005 2021-03-31
008 2018 bl uuuu u01u1 u #d
100 1 $aNAVAJAS, E.
245 $aAccuracy of genomic predictions for carcass and meat quality traits in the Uruguayan Hereford breed.$h[electronic resource]
260 $aIn: Proceedings of the World Congress on Genetics Applied to Livestock Production, 11., Aotea Centre Auckland, New Zealand: WCGALP, ICAR, 11-16 feb 2018.$c2018
300 $a6 p.
500 $aAcknowledgements: This work was supported by the Agencia Nacional de Investigación e Innovación (ANII) (grants RTS_1_2012_1_3489 and FMV_1_2011_1_6671), Instituto Nacional de Investigación Agropecuaria (INIA), Sociedad de Criadores de Hereford (SCH), Instituto Nacional de Carnes (INAC) and Asociación Rural del Uruguay (ARU).
520 $aSUMMARY. Genomic selection provides the opportunity of genetic improvement of difficult-to-measure traits, such as carcass and meat traits. This study investigated the accuracies of genomic predictions of carcass and meat quality traits in Hereford with an initial training population of 747 steers. Hot carcass weights, rib eye areas and subcutaneous, fat depths were recorded in commercial slaughterhouses, as well as, the left pistola cut weight and retail product. Shear force and intramuscular fat content were measured in the Longissumus dorsi.
653 $aBeef cattle
653 $aCarcass quality
653 $aGenomic selection
653 $aMeat quality
653 $aPredictability
700 1 $aMACEDO, F.
700 1 $aLEMA, O.M.
700 1 $aLUZARDO, S.
700 1 $aAGUILAR, I.
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